abberior News

abberior news

superhot superresolution

abberior and the European Molecular Biology Laboratory (EMBL) have launched a collaboration on the application of MINFLUX in biology. The goal of this agreement is to combine forces regarding further development of the method, and to apply superresolution MINFLUX microscopy to living systems.

To this end, abberior installed a MINFLUX system at the EMBL Imaging Centre in Heidelberg, Germany in August 2020. This nanoscope will be used for developing imaging workflows and for targeting a broad range of biological questions. After successful proof-of-concept applications, the system will also be available for external users in the framework of the new EMBL Imaging Centre.

“This collaboration will allow us to apply MINFLUX to highly relevant questions in biology and to push the limits of this technology. In the near future, we will to adapt MINFLUX microscopy to operate in living systems.” said Christian Wurm, Head of the abberior application team.

The abberior MINFLUX system is the newest addition to the abberior product portfolio. It is the first commercialized microscopy system that provides true molecule-size resolution and holds the world-record in temporal resolution for single particle tracking.

 

Abberior has opened its new office in Bethesda, Maryland, USA. The new site houses conference and showrooms, demo rooms and offices, as well as a supply for replacement parts.

“Abberior Instruments America is excited to have opened our new office in Bethesda Maryland located less than 1 mile from the National Institutes of Health main campus and within a short drive of key research centers at Johns Hopkins and Howard Hughes’ Janelia Farms.” says David Melton, CEO of Abberior Instruments America.

Our US staff and two microscopes, a FACILITY line and a STEDYCON, are looking forward to our customers, many interesting discussions, live and remote demos, and exceptional images.

Using an abberior STED-FCS, a team from four European countries, comprising Christian Eggeling (Leibniz IPHT & Friedrich Schiller University Jena) and Delphine Muriaux (Montpellier Infectious Disease Research Institute) discovered the existence and composition of a lipid-based platform for HIV virus assembly. These results provide novel molecular insights on HIV virus assembly and are a starting point for the development of new antiviral drugs.

 

Read here: “HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly”Science Advances

In this article, Prof. Stefan Hell talks about his professional career, how he came to develop STED microscopy in the early nineties, and how our company was started and where it’s heading.

It’s a fantastic read about the early times of superresolution all the way up to now, with many interesting details about why things unfolded in a particular way. Don’t miss it if you’re interested in the history of STED, abberior, or Stefan Hell!

 

Further Information:
Website Max Planck
Full Article (German)

Scientists in France have successfully used an abberior STED system and abberior dyes to shoot images of SARS-CoV2 (“Corona”, magenta) infecting VeroE6 cells.

Understanding the precise structure of this virus and the processes during and after infection are crucial to finding a cure or vaccine, ending lockdowns all around the world. Standard light microscopes are not of much help, since they are limited by diffraction (approx. 200 nm), while the virus particles have a much smaller diameter at about 100 nm. Because of this, SARS-CoV2 and important cellular structures that it attacks only show up blurry in standard, e.g. so-called confocal microscopes.

In the past, electron microscopy would have been used, but sample preparation for this instruments in tedious and they cannot image living matter, which is nevertheless vital to unraveling the workings of a corona infection on the cellular level. This is where STED microscopy comes into play: with a resolution 5-10 times below the diffraction limit, and much weaker constraints regarding sample preparation, it’s going to be an important tool for finding drugs against corona and similar viruses.

 

Copyright: MDVA team/CNRS Montpellier, France (D. Muriaux, C. Favard, M.-P. Blanchard @MRI)

Abberior, the leading STED solution provider from the inventors of STED and Nikon Instruments Inc., innovator of advanced microscope systems today announced a strategic partnership to accelerate adoption of easy-to-use STED technology in the US. As part of this collaboration, abberior’s compact STEDYCON system will be distributed by Nikon.

Inquiries for Abberior Instruments America: David Melton | CEO | 561.972.9300 | info@abberior-instruments-america.com

Media Inquiries for Nikon Instruments Inc.: Kristina Corso | Communications Specialist | 212.931.6189 | kcorso@hotpaperlantern.com

Further Information

 

When we started our business in 2012 in a small office ‘garage’ in Göttingen, our vision was to become the technically leading manufacturer for superresolution microscopes worldwide. With currently around 50 employees in Heidelberg (Germany), Jupiter (Florida, USA) as well as in Basel (Switzerland), we have turned into a globally recognized maker of superresolution light microscopes, selling in more than 35 countries. Due to the excellence of our highly selected and skilled team we have been able to grow with remarkable speed, and now we’re officially recognized as a growth champion!

With fourth place in the category “manufacturing industry”*, and ranked number 133th of 500 companies nationwide, we are very proud to be part of the “Wachstumschampions 2019”. Our average growth between 2014 and 2017 was almost 60% per year.

The Focus ranking lists companies that have achieved the highest sales growth per year in the last three years. Statista sieved through thousands of companies with above-average growth from more than 2 million commercial register entries, and invited many more to apply for the 2019 Growth Championships. The companies now listed in the Focus magazine’s top list are the ones that received the “Growth Champion 2019” award.

 

Further Information

*without automobile, machinery and plant construction industry